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The Regents of the University of California, San Francisco

Improve oral health and prevent blood stream infection using novel biopolymers

Project Type: 
Research/Medically Compromised
Amount Awarded: 
Grant Type: 
DTA Foundation


We aim to develop conjugated biopolymers and/or biomimetic polymers, such as a new category of peptide-like polymers (peptoids) to target and bind specific bacteria causing BSI, primarily S. mitis, and Escherichia coli/E.coli as a well known BSI causing model bacteria. When added to a mouthwash, cleansing gel, or pad, these polymers would selectively bind to and block bacteria binding, and prevent biofilm formation consequently.